His fields of specialty is infectious disease epidemiology and research interests include evaluation of population based HIV intervention and clinical management of HIV.
He is the founder of the Rakai Health Science Program, RHSP, which has pioneered research of HIV and how it is transmitted. Today the program includes 650 support staff and multidisciplinary investigators that have conducted high impact research with huge public health implication. Dr. Serwadda has published over 350 publication in medical journals and book chapters. He is the international Principal investigator to HIV Prevention Trial Network, HPTN and an investigator in several projects in the school, including METS, Fellowship program. He is a member of the international editors of the Lancet HIV, a regular reviewer for the New England Journal of Medicine and AIDS journals. Dr Serwadda is a member of Board of trustee on several international organizations.