CRMP4 regulates dendritic growth and maturation via the interaction with actin cytoskeleton in cultured hippocampal neurons
Brain Research Bulletin(2016)
摘要
•CRMP4 is sufficient and necessary for the dendritic growth and maturation in cultured hippocampal neurons.•CRMP4 functions via the interaction with the actin cytoskeleton by the C-terminal.•CRMP4 is critical for spine maturation in cultured hippocampal neurons.
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关键词
CRMP4,Actin,Dendritic development,Spine,mEPSC,Hippocampal neuron
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