Apolipoprotein A‐1 Protected Hepatic Ischaemia–reperfusion Injury Through Suppressing Macrophage Pyroptosis Via TLR4–NF‐κB Pathway

LIVER INTERNATIONAL（2023）

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摘要
Apolipoprotein A‐1 (ApoA‐1), the major apolipoprotein of high‐density lipoprotein, plays anti‐atherogenic role in cardiovascular diseases and exerts anti‐inflammation effect in various inflammatory and infectious diseases. However, the role and mechanism of ApoA‐1 in hepatic ischaemia–reperfusion (I/R) injury is unknown.
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关键词
ApoA-1,hepatic ischaemia-reperfusion injury,macrophage,pyroptosis,TLR4-NF-kappa B
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