89P A Clinical- and Biological-Based Nomogram to Predict Unforeseen Nodal Metastases in Clinically Node-Negative, Radically Resected Lung Adenocarcinoma

Despite an adequate preoperative staging, unexpected nodal metastases after surgery are detected in a relevant number of cases. Given the promising role of novel neoadjuvant treatments, the definition of predictive factors for nodal metastases is critical. In this study we aim to analyze the clinical and molecular factors associated with upstaging in patients with early stage LUAD without evidence of nodal disease in the preoperative staging who underwent lobectomyand radical lymphadenectomy.