Analysis of the Safety and Effectiveness of TACE Combined with Targeted Immunotherapy in the Treatment of Intermediate and Advanced Hepatocellular Carcinoma.

MEDICAL ONCOLOGY(2023)

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摘要
To evaluate the effectiveness and safety of transarterial chemoembolization (TACE) combined with immune and targeted therapy in unresectable hepatocellular carcinoma (HCC). Prospective analysis of 23 patients with intermediate or advanced primary HCC treated at the Department of Hepatic Surgery, The First Affiliated Hospital of the University of Science and Technology of China from July 2019, including 11 cases treated with TACE alone and 12 cases treated with TACE combined with targeted therapy. The basal indexes of patients in the two groups were compared, and the response during treatment was observed; regular follow-up was performed to assess the efficacy of tumor treatment. Compared with TACE treatment alone, the objective response rate (ORR) was significantly higher in the TACE combined with targeted treatment group (50.0
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关键词
Hepatocellular carcinoma,Transarterial chemoembolization,Translational therapy,Targeted therapy,Immunotherapy
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