Partial heart transplantation: Growing heart valve implants for children

Heart valves serve a vital hemodynamic function to ensure unidirectional blood flow. Additionally, native heart valves serve biological functions such as growth and self-repair. Heart valve implants mimic the hemodynamic function of native heart valves, but are unable to fulfill their biological functions. We developed partial heart transplantation to deliver heart valve implants that fulfill all functions of native heart valves. This is particularly advantageous for children, who require growing heart valve implants. This invited review outlines the past, present and future of partial heart transplantation. Heart valve replacement in babies is marred with problems because heart valve implants do not grow. Partial heart transplantation is a new approach to deliver growing heart valve implants. This invited review outlines the past, present, and future of partial heart transplantation.image