Effectiveness of Subjective Support-Focused Cognitive Behavioral Therapy on Depressive Symptoms among (pre)frail Community-Dwelling Older Adults: A Randomized Controlled Trial.

Background: Subjective support could ameliorate the adverse effect of (pre)frailty on depressive symptoms. However, there is scarce evidence regarding subjective support-focused intervention in preventing depression among (pre)frail community-dwelling older adults. This study aims to explore the effectiveness of subjective support-focused cognitive behavioral therapy (SS-CBT) in preventing depression among this group of population.Methods: A total of 100 community-dwelling (pre)frail older adults were recruited from six communities in a Chinese city and were randomized to an 8-week SS-CBT group or a wait-list control group. Depressive symptoms and subjective support were assessed at baseline (T0), and at 8 week (T1), 12 week (T2), 16 week (T3) after randomization. Generalized estimating equation was used to examine the effectiveness of SS-CBT on depressive symptoms and subjective support. Hierarchical linear regression models and Bootstrapping method were used to examine whether subjective support mediated the effectiveness of SS-CBT on depressive symptoms. Results: Participants in SS-CBT group reported significant reduction in depressive symptoms (Wald chi 2 = 20.800, p < 0.001) and improvement in subjective support (Wald chi 2 = 92.855, p < 0.001) compared to those in wait-list control group. Changes in subjective support mediated the effectiveness of SS-CBT on changes in depressive symptoms.Limitations: Restricted regions to recruit participants, inclusion of the most motivated participants, lack of diagnosis of depression, potential experimenter bias and contamination, short follow-up period, and lack of an active control group.Conclusions: The findings support the benefits of SS-CBT in preventing depression among (pre)frail communitydwelling older adults, and provide insight into possible mechanisms.