PsoBioVax: A Multicentric Italian Case-Control Study of the Immunological Response to Anti-Sars-cov-2 Vaccine among Psoriatic Patients under Biological Therapy

Journal of the European Academy of Dermatology and VenereologyEarly View LETTER TO THE EDITOR PsoBioVax: A multicentric Italian case–control study of the immunological response to anti-SARS-CoV-2 vaccine among psoriatic patients under biological therapy L. Sacchelli, Corresponding Author L. Sacchelli [email protected] orcid.org/0000-0003-4388-4523 Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy Correspondence M. A. Chessa and L. Sacchelli, Via G. Massarenti, 1, 40138 Bologna, Italy. Email: [email protected]; [email protected]Search for more papers by this authorF. Filippi, F. Filippi orcid.org/0000-0001-8173-4257 Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, ItalySearch for more papers by this authorA. Balato, A. Balato orcid.org/0000-0001-5485-0172 Unit of Dermatology, University of Campania Luigi Vanvitelli, Naples, ItalySearch for more papers by this authorR. Balestri, R. Balestri orcid.org/0000-0002-0885-054X Division of Dermatology, Psoriasis Outpatient Service, APSS, Trento, ItalySearch for more papers by this authorF. Bellinato, F. Bellinato orcid.org/0000-0002-6163-6921 Dipartimento di Medicina Sezione Di Dermatologia Università di Verona, Verona, ItalySearch for more papers by this authorN. Bernardini, N. Bernardini orcid.org/0000-0002-6295-3574 Department of Medico-Surgical Sciences and Biotechnologies Faculty of Pharmacy and Medicine Sapienza University of Rome – Polo Pontino (ASL Latina), Latina, ItalySearch for more papers by this authorL. Bianchi, L. Bianchi Dermatology, University of Rome Tor Vergata, Rome, ItalySearch for more papers by this authorM. Burlando, M. Burlando orcid.org/0000-0002-4381-6718 Department of Dermatology, DISSAL University of Genoa, IRCCS Ospedale Policlinico San Martino, Genova, ItalySearch for more papers by this authorA. Campanati, A. Campanati orcid.org/0000-0002-3740-0839 Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, Ancona, ItalySearch for more papers by this authorM. A. Chessa, Corresponding Author M. A. Chessa [email protected] orcid.org/0000-0002-0149-8870 Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy Correspondence M. A. Chessa and L. Sacchelli, Via G. Massarenti, 1, 40138 Bologna, Italy. Email: [email protected]; [email protected]Search for more papers by this authorM. Corazza, M. Corazza Department of Medical Sciences, Section of Dermatology and Infectious Diseases, University of Ferrara, Ferrara, ItalySearch for more papers by this authorA. Di Cesare, A. Di Cesare orcid.org/0000-0002-1001-4604 Department of Health Sciences, Section of Dermatology, University of Florence, Florence, ItalySearch for more papers by this authorV. Di Lernia, V. Di Lernia Dermatology Unit, Arcispedale Santa Maria Nuova, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, ItalySearch for more papers by this authorF. Diotallevi, F. Diotallevi Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, Ancona, ItalySearch for more papers by this authorM. Esposito, M. Esposito orcid.org/0000-0002-4773-6993 Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy Dermatology Unit, Ospedale San Salvatore, L'Aquila, ItalySearch for more papers by this authorM. C. Fargnoli, M. C. Fargnoli orcid.org/0000-0002-7249-2556 Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy Dermatology Unit, Ospedale San Salvatore, L'Aquila, ItalySearch for more papers by this authorP. Gisondi, P. Gisondi orcid.org/0000-0002-1777-9001 Dipartimento di Medicina Sezione Di Dermatologia Università di Verona, Verona, ItalySearch for more papers by this authorA. Giunta, A. Giunta orcid.org/0000-0003-3589-9346 Dermatology, Fondazione PTV Policlinico Tor Vergata, Rome, ItalySearch for more papers by this authorK. Hansel, K. Hansel orcid.org/0000-0002-6674-4278 Dermatology Section, Department of Medicine and Surgery, University of Perugia, Perugia, ItalySearch for more papers by this authorM. Magnano, M. Magnano orcid.org/0000-0001-9429-9004 Division of Dermatology, Psoriasis Outpatient Service, APSS, Trento, ItalySearch for more papers by this authorM. Megna, M. Megna orcid.org/0000-0003-1803-2046 Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Napoli, ItalySearch for more papers by this authorG. Odorici, G. Odorici orcid.org/0000-0002-5910-8994 Department of Medical Sciences, Section of Dermatology and Infectious Diseases, University of Ferrara, Ferrara, ItalySearch for more papers by this authorF. Prignano, F. Prignano orcid.org/0000-0002-5997-2045 Department of Health Sciences, Section of Dermatology, University of Florence, Florence, ItalySearch for more papers by this authorC. Potenza, C. Potenza Department of Medico-Surgical Sciences and Biotechnologies Faculty of Pharmacy and Medicine Sapienza University of Rome – Polo Pontino (ASL Latina), Latina, ItalySearch for more papers by this authorG. Rech, G. Rech Division of Dermatology, Psoriasis Outpatient Service, APSS, Trento, ItalySearch for more papers by this authorM. Rovesti, M. Rovesti Dermatologic Unit, Ospedale “Guglielmo da Saliceto”, Piacenza, PC, ItalySearch for more papers by this authorA. Ruggiero, A. Ruggiero orcid.org/0000-0002-4658-7391 Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Napoli, ItalySearch for more papers by this authorF. Satolli, F. Satolli UOC Dermatologia, University of Parma, Parma, ItalySearch for more papers by this authorL. Stingeni, L. Stingeni orcid.org/0000-0001-7919-8141 Dermatology Section, Department of Medicine and Surgery, University of Perugia, Perugia, ItalySearch for more papers by this authorD. Gibertoni, D. Gibertoni orcid.org/0000-0002-1722-3724 Research and Innovation Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalySearch for more papers by this authorF. Bardazzi, F. Bardazzi Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, ItalySearch for more papers by this author L. Sacchelli, Corresponding Author L. Sacchelli [email protected] orcid.org/0000-0003-4388-4523 Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy Correspondence M. A. Chessa and L. Sacchelli, Via G. Massarenti, 1, 40138 Bologna, Italy. Email: [email protected]; [email protected]Search for more papers by this authorF. Filippi, F. Filippi orcid.org/0000-0001-8173-4257 Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, ItalySearch for more papers by this authorA. Balato, A. Balato orcid.org/0000-0001-5485-0172 Unit of Dermatology, University of Campania Luigi Vanvitelli, Naples, ItalySearch for more papers by this authorR. Balestri, R. Balestri orcid.org/0000-0002-0885-054X Division of Dermatology, Psoriasis Outpatient Service, APSS, Trento, ItalySearch for more papers by this authorF. Bellinato, F. Bellinato orcid.org/0000-0002-6163-6921 Dipartimento di Medicina Sezione Di Dermatologia Università di Verona, Verona, ItalySearch for more papers by this authorN. Bernardini, N. Bernardini orcid.org/0000-0002-6295-3574 Department of Medico-Surgical Sciences and Biotechnologies Faculty of Pharmacy and Medicine Sapienza University of Rome – Polo Pontino (ASL Latina), Latina, ItalySearch for more papers by this authorL. Bianchi, L. Bianchi Dermatology, University of Rome Tor Vergata, Rome, ItalySearch for more papers by this authorM. Burlando, M. Burlando orcid.org/0000-0002-4381-6718 Department of Dermatology, DISSAL University of Genoa, IRCCS Ospedale Policlinico San Martino, Genova, ItalySearch for more papers by this authorA. Campanati, A. Campanati orcid.org/0000-0002-3740-0839 Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, Ancona, ItalySearch for more papers by this authorM. A. Chessa, Corresponding Author M. A. Chessa [email protected] orcid.org/0000-0002-0149-8870 Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy Correspondence M. A. Chessa and L. Sacchelli, Via G. Massarenti, 1, 40138 Bologna, Italy. Email: [email protected]; [email protected]Search for more papers by this authorM. Corazza, M. Corazza Department of Medical Sciences, Section of Dermatology and Infectious Diseases, University of Ferrara, Ferrara, ItalySearch for more papers by this authorA. Di Cesare, A. Di Cesare orcid.org/0000-0002-1001-4604 Department of Health Sciences, Section of Dermatology, University of Florence, Florence, ItalySearch for more papers by this authorV. Di Lernia, V. Di Lernia Dermatology Unit, Arcispedale Santa Maria Nuova, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, ItalySearch for more papers by this authorF. Diotallevi, F. Diotallevi Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, Ancona, ItalySearch for more papers by this authorM. Esposito, M. Esposito orcid.org/0000-0002-4773-6993 Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy Dermatology Unit, Ospedale San Salvatore, L'Aquila, ItalySearch for more papers by this authorM. C. Fargnoli, M. C. Fargnoli orcid.org/0000-0002-7249-2556 Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy Dermatology Unit, Ospedale San Salvatore, L'Aquila, ItalySearch for more papers by this authorP. Gisondi, P. Gisondi orcid.org/0000-0002-1777-9001 Dipartimento di Medicina Sezione Di Dermatologia Università di Verona, Verona, ItalySearch for more papers by this authorA. Giunta, A. Giunta orcid.org/0000-0003-3589-9346 Dermatology, Fondazione PTV Policlinico Tor Vergata, Rome, ItalySearch for more papers by this authorK. Hansel, K. Hansel orcid.org/0000-0002-6674-4278 Dermatology Section, Department of Medicine and Surgery, University of Perugia, Perugia, ItalySearch for more papers by this authorM. Magnano, M. Magnano orcid.org/0000-0001-9429-9004 Division of Dermatology, Psoriasis Outpatient Service, APSS, Trento, ItalySearch for more papers by this authorM. Megna, M. Megna orcid.org/0000-0003-1803-2046 Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Napoli, ItalySearch for more papers by this authorG. Odorici, G. Odorici orcid.org/0000-0002-5910-8994 Department of Medical Sciences, Section of Dermatology and Infectious Diseases, University of Ferrara, Ferrara, ItalySearch for more papers by this authorF. Prignano, F. Prignano orcid.org/0000-0002-5997-2045 Department of Health Sciences, Section of Dermatology, University of Florence, Florence, ItalySearch for more papers by this authorC. Potenza, C. Potenza Department of Medico-Surgical Sciences and Biotechnologies Faculty of Pharmacy and Medicine Sapienza University of Rome – Polo Pontino (ASL Latina), Latina, ItalySearch for more papers by this authorG. Rech, G. Rech Division of Dermatology, Psoriasis Outpatient Service, APSS, Trento, ItalySearch for more papers by this authorM. Rovesti, M. Rovesti Dermatologic Unit, Ospedale “Guglielmo da Saliceto”, Piacenza, PC, ItalySearch for more papers by this authorA. Ruggiero, A. Ruggiero orcid.org/0000-0002-4658-7391 Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Napoli, ItalySearch for more papers by this authorF. Satolli, F. Satolli UOC Dermatologia, University of Parma, Parma, ItalySearch for more papers by this authorL. Stingeni, L. Stingeni orcid.org/0000-0001-7919-8141 Dermatology Section, Department of Medicine and Surgery, University of Perugia, Perugia, ItalySearch for more papers by this authorD. Gibertoni, D. Gibertoni orcid.org/0000-0002-1722-3724 Research and Innovation Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalySearch for more papers by this authorF. Bardazzi, F. Bardazzi Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, ItalySearch for more papers by this author First published: 07 December 2023 https://doi.org/10.1111/jdv.19662 L. Sacchelli and F. Filippi contributed equally. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Open Research DATA AVAILABILITY STATEMENT The data that support the findings of this study are available on request from the corresponding author, MAC. The data are not publicly available due to their containing information that could compromise the privacy of research participants. REFERENCES 1Hansun S, Charles V, Gherman T. The role of the mass vaccination programme in combating the COVID-19 pandemic: an LSTM-based analysis of COVID-19 confirmed cases. Heliyon. 2023; 9(3):e14397. https://doi.org/10.1016/j.heliyon.2023.e14397 10.1016/j.heliyon.2023.e14397 PubMedWeb of Science®Google Scholar 2Wack S, Patton T, Ferris LK. COVID-19 vaccine safety and efficacy in patients with immune-mediated inflammatory disease: review of available evidence. J Am Acad Dermatol. 2021; 85(5): 1274–1284. https://doi.org/10.1016/j.jaad.2021.07.054 10.1016/j.jaad.2021.07.054 CASPubMedWeb of Science®Google Scholar 3Cristaudo A, Graceffa D, Pimpinelli F, Sperati F, Spoletini G, Bonifati C, et al. Immunogenicity and safety of anti-SARS-CoV-2 BNT162b2 vaccine in psoriasis patients treated with biologic drugs. J Eur Acad Dermatol Venereol. 2022; 36(4): e266–e268. https://doi.org/10.1111/jdv.17861 10.1111/jdv.17861 CASPubMedWeb of Science®Google Scholar 4Al-Janabi A, Littlewood Z, Griffiths CEM, Hunter HJA, Chinoy H, Moriarty C, et al. Antibody responses to single-dose SARS-CoV-2 vaccination in patients receiving immunomodulators for immune-mediated inflammatory disease. Br J Dermatol. 2021; 185(3): 646–648. https://doi.org/10.1111/bjd.20479 10.1111/bjd.20479 CASPubMedWeb of Science®Google Scholar 5Nah EH, Cho S, Park H, Kim S, Noh D, Kwon E, et al. SARS-CoV-2 antibody response and sustainability after a third dose of BNT162b2 in Healthcare Workers at Health Promotion Centers. Viruses. 2023; 15: 751. 10.3390/v15030751 CASPubMedGoogle Scholar 6Chiricozzi A, Gisondi P, Bellinato F, Girolomoni G. Immune response to vaccination in patients with psoriasis treated with systemic therapies. Vaccines. 2020; 8(4):769. https://doi.org/10.3390/vaccines8040769 10.3390/vaccines8040769 CASWeb of Science®Google Scholar 7Talamonti M, Galluzzo M. Safety of COVID-19 vaccines in patients with psoriasis undergoing therapy with anti-interleukin agents. Expert Opin Biol Ther. 2021; 21(11): 1535–1537. https://doi.org/10.1080/14712598.2021.1965985 10.1080/14712598.2021.1965985 CASPubMedWeb of Science®Google Scholar 8Musumeci ML, Caruso G, Trecarichi AC, Micali G. Safety of SARS-CoV-2 vaccines in psoriatic patients treated with biologics: a real life experience. Dermatol Ther. 2022; 35:e15177. https://doi.org/10.1111/dth.15177 10.1111/dth.15177 CASPubMedWeb of Science®Google Scholar 9Valencia López M, Meineke A, Stephan B, et al. SARS-CoV-2 vaccination status and adverse events among patients with psoriasis – data from the German registries PsoBest and CoronaBest. J Eur Acad Dermatol Venereol. 2023; 37: e831–e833. https://doi.org/10.1111/jdv.19039 10.1111/jdv.19039 PubMedWeb of Science®Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation