Treatment with Direct Oral Anticoagulants (doacs) and Secondary Prophylaxis in Patients Affected by Multiple Episodes of Superficial Venous Thrombosis.

Superficial vein thrombosis (SVT) describes partial or total thrombotic lumen obstruction of a superficial vein and inflammatory alterations of the affected vessel wall [1]. The precise incidence of SVT is unknown, but it is likely more prevalent than deep vein thrombosis (DVT). The most frequently involved sites for SVT are the lower limbs. Historically, SVT was considered a self-limiting condition. However, nowadays a significant risk (around 10 %) of propagation into the deep veins, leading to DVT or pulmonary embolism (PE) within 90 days, is recognized if SVT is not treated [1].