Generation and Characterization of Human IgE Mabs to PR-10 Allergens

Scott Smith, Joshua Doyle,Jonas Lidholm,Ronald Van Ree大牛学者,Lorenz Aglas,Andrea O'Malley,Maksymilian Chruszcz, Jian Zhang,Stokes Peebles大牛学者

Journal of Allergy and Clinical Immunology（2024）

引用 0|浏览18

摘要

Due to the very low concentration and polyclonal nature of IgE in peripheral blood, the fine molecular detail underlying allergy has been difficult to study. Human monoclonal antibodies (mAbs) obtained from subjects with allergic rhinitis will now allow comprehensive characterization of the major allergens involved in these responses.

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