WCN24-1274 THE EFFECT OF LACTOFERRIN ON HEMOGLOBIN, ERYTHROFERRONE AND HEPCIDIN LEVELS IN CHRONIC KIDNEY DISEASE

Anemia continues to be a common complication in chronic kidney disease (CKD) population despite optimum treatment with adequate dialysis, erythropoietin and repletion of nutrient deficiencies. As shown via our other abstract presented at WCN 2024, lactoferrin has antiinflammatory properties and plays a major role in improvement of hemoglobin, absorption and utilization of iron. Erythroferrone is a hormone that is increased as the body's response to anemia and improves hemoglobin (Hb) levels. Among other mechanisms for improving erythropoiesis, the most putative mechanism of erythroferrone is by decreasing hepcidin.