Activities of Daily Living in Older Individuals with Chronic Kidney Disease：what Factors Might Influence It?

Older individuals with chronic kidney disease (CKD) experience a significant decline in their ability to perform activities of daily living (ADLs). This study aimed to investigate the factors associated with decreased ADLs in older individuals with CKD. A cross-sectional study was conducted between 1 September 2013 and 30 June 2014 at the West China Hospital of Sichuan University and Kangfu Kidney Disease Hospital in Chengdu. The study encompassed individuals with CKD who were aged > 60 years. Each participant underwent a comprehensive geriatric assessment by trained doctors. In the univariate analysis, significant statistical differences (P < 0.05) were observed in several factors, including age, marital status, serum albumin levels, risk of malnutrition, malnutrition, cognitive function, depression scores, comorbidity index, subjective support, and the use of social support. Multiple logistic regression analysis revealed that independent factors associated with impaired ADLs in older individuals with CKD included age (odds ratio [OR] = 1.81, 95% confidence interval [CI]: 1.01–3.25 for ages 70–79 years; OR = 5.42, 95% CI: 2.99–9.81 for ages ≥ 80 years), widowhood (OR = 1.90, 95% CI: 1.15–3.15), depression (OR = 1.33, 95% CI: 1.22–1.44), risk of malnutrition (OR = 2.81, 95% CI: 1.70–4.65), and malnutrition (OR = 5.13, 95%CI: 2.51–10.50).