TET2 Mutation in Acute Myeloid Leukemia: Biology, Clinical Significance, and Therapeutic Insights
Clinical epigenetics（2024）
摘要
TET2 is a critical gene that regulates DNA methylation, encoding a dioxygenase protein that plays a vital role in the regulation of genomic methylation and other epigenetic modifications, as well as in hematopoiesis. Mutations in TET2 are present in 7
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关键词
TET2,Acute myeloid leukemia,DNA methylation,Mechanisms,Therapeutic insights
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