She is a clinical investigator with primary focus on the etiology and primordial prevention of obesity and related co-morbidities, particularly type 2 diabetes and gestational diabetes. Her interests also include fetal metabolic programming mechanisms and the integration of genetics, epigenetics, and environmental factors contributing to obesity and related disorders. She is the Principal Investigator (PI) of Genetics of Glucose regulation In Gestation and Growth (Gen3G), and co-PI of Project Viva, two independent prospective pre-birth cohorts that investigate the health determinants of mothers and children. She is currently involved in many international consortia investigating the genetics determinants of glycemic regulation during and outside of pregnancy, as well as epigenetics mechanisms linked to prenatal exposures and fetal programming. At Harvard Medical School, she is the director of the Curricular Theme “Nutrition and Lifestyle Medicine” and the co-director of the Advanced Integrated Science Course “Metabolism, Nutrition, and Lifestyle Medicine”.